Comorbidity between temporal lobe epilepsy and depression: a [F]MPPF PETstudy
نویسندگان
چکیده
CTRS-IDEE, Hospices Civils de Lyon, INSERM U821, University Claude Bernard Lyon 1 and Neuroscience Federative Institute of Lyon, Lyon, Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, INSERMU879, University Claude Bernard Lyon 1 and Neuroscience Federative Institute of Lyon, Lyon, France, Department of Clinical Neuroscience, Division of Neuroscience and Mental Health, Imperial College, London, UK, CERMEP-imagerie du vivant, EA4166 and CH leVinatier, University Claude Bernard Lyon 1 and Neuroscience Federative Institute of Lyon, Lyon, France and Department of Neurology, Columbia University, NewYork, NY, USA
منابع مشابه
Comorbidity between temporal lobe epilepsy and depression: a [18F]MPPF PET study.
Brain and brainstem changes of serotoninergic 5-hydroxytryptophan (5-HT)(1A) receptor density have been reported in patients with major depressive disorder as well as in patients with temporal lobe epilepsy (TLE), using PET and the selective antagonist radiotracers [(11)C]WAY-100635 or [(18)F]FC-WAY. We used a distinct 5-HT(1A) antagonist, [(18)F]MPPF, whose binding potential depends on both re...
متن کاملPET imaging of brain 5-HT1A receptors in the preoperative evaluation of temporal lobe epilepsy.
[(18)F]MPPF PET has previously been used to identify the epileptic lobe in temporal lobe epilepsy (TLE) patients at the group level. This study aims to validate the visual analysis of [(18)F]MPPF PET in the assessment of individual TLE patients for their suitability to undergo temporal lobe resection. Forty-two patients suffering from TLE and 18 control subjects matched for age and gender were ...
متن کاملP163: Prevalence of Depression and Anxiety in Epileptic Patients
Anxiety and depression are very common in population and occur in a wide range of clinical states and is very common in epileptic patients. Many recent epidemiological studies have found a high prevalence of depression and anxiety in epileptic patients. These studies found that epileptic patients suffered from depression and anxiety than those without epilepsy. The prevalence of depression or a...
متن کاملIctal and Interictal Electroencephalography of Mesial and Lateral Temporal Lobe Epilepsy; A Comparative Study
Background: Epilepsy is considered as one of the most important disorders in neurology. Temporal lobe epilepsy is a form of epilepsy including two main types of mesial and lateral (neocortex). Objectives: Determination and comparison of electroencephalogram (EEG) pattern in the ictal and interictal phases of mesial and lateral temporal lobe epilepsy. Materials and Methods: This cross-sectiona...
متن کاملP119: Animal Models of Epilepsy: The Impact of some Chemoconvalsants on Animal Models
We summarize some of the most frequenthly used rodent animal models of temporal lobe epileps and the impact of chemoconvulsants on them. Temporal lobe epilepsy is the most common epilepsy in humans in which seizures spread to the neighboring cortiase and hippocampal neuron loss and other neuropathological take place. Temporal lobe epilepsy and the other form of epilepsy cannot acquired in chini...
متن کامل